Free Case Study

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

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Diagnosis: Chondroma Arising in Pleomorphic Adenoma of minor Salivary Gland

Literature: Chondroma of the parotid gland is an extremely rare type of tumor that consists of benign mature cartilage arising in the parotid gland with no admixture of epithelial and myoepithelial components. Strict morphologic criteria are required to diagnose a parotid chondroma. The entire specimen should be submitted and sections prepared from multiple levels should be examined to exclude a pleomorphic adenoma. A parotid chondroma should be located within the parotid gland and should be composed purely of cartilage. Atypia, increased mitoses, and necrosis should not be present. Since tumors of the parotid gland have a 5.5% to 25% recurrence rate, and also have a remote possibility of malignant transformation, wide local surgical excision is generally recommended; however, there are no current treatment recommendations specific for parotid chondromas due to their extreme rarity.

 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate

 

 

pcs casesDiagnosis of malignant parotid tumor was given on FNAC.Resection of the tumor was carried out and specimen was received. Gross examination revealed mass 6x4x3 cm in size, soft to firm in consistency and reddish in colour. Cut surface should indistinct grayish white nodules of variable size coalescing at places. Microscopy: Microscopic examination revealed malignant tumor involving parotid gland. Malignant cells were arranged around empty spaces cells were epithelioid in nature and projected into the lumina in some areas. Some cells should intracytoplasmic lumina. Some cells showed bizarre nuclei.Mitotic A­ activity was high. Tumour necrosis was present.Provisional Diagnosis of Angiosarcoma was made and parotid carcinoma, unclassifiable was kept in the differential diagnosis. 

pcs cases

 

Click to see Digital Slide

Diagnosis result shown here
 

pcs cases75 Year, Male presented with swelling in the right parotid region of 6 months duration. The swelling was about 5x4 cm in size and firm to hard in consistency.Patient gave past history of resection of grade I-II transitional cell carcinoma, urinary bladder two years back. Aspiration was carried out from parotid swelling. Very large anaplastic cells were present in the aspirate