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The collection device is important for ensuring sample adequacy. A variety of devices are available for obtaining conventional cervical samples such as wooden/plastic spatula, “broom-type” samplers and endocervical brushes that may be used depending upon the clinical situation. The use of cotton-tipped swab is not recommended. A single sample obtained with either a spatula or “broom-type” brush should be adequate if the transformation zone is visible. However, if the TZ is not visualized as in postmenopausal woman or following previous cervical treatment, endocervical brush should be used to obtain endocervical sample in addition to the ectocervical. In pregnant woman, an endocervical brush should be avoided.